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 Formulary Chapter 7: Obstetrics, Gynaecology, and urinary-tract disorders - Full Chapter
07.01  Drugs used in obstetrics
07.01.01  Prostaglandins and oxytocics
Dinoprostone
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First Choice Pessaries (Propess)
Vaginal Tablets (Prostin E2
Carboprost (Hemabate)
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Formulary Injection 
   
Ergometrine Maleate
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Formulary Injection 
   
Ergometrine Maleate and Oxytocin (Syntometrine)
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Formulary Injection 
   
Oxytocin (Syntocinon)
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Formulary Injection 
   
Gemeprost
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Formulary Pessaries 
   
Misoprostol
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Formulary Tablets (for oral or vaginal administration)
unlicensedUnlicensed indication 
Link  PAT Guideline: Medical termination of pregnancy
   
07.01.01.01  Drugs affecting the ductus arteriosus
07.01.01.01  Maintenance of patency
07.01.01.01  Closure of ductus arteriosus to top
Ibuprofen (Pedea)
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Formulary Intravenous solution 
   
Indometacin
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Formulary Injection 
   
07.01.02  Mifepristone
Mifepristone (Mifegyne)
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Formulary Tablets 
Link  PAT Guideline: Medical termination of pregnancy
   
07.01.03  Myometrial relaxants
Nifedipine
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First Choice Capsules
unlicensedUnlicensed indication 
Indometacin
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Second Choice Suppositories
Capsules
unlicensedUnlicensed indication 
   
Atosiban (Tractocile)
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Restricted Drug Restricted Not to be initiated at Pennine Acute Trust 
   
Salbutamol
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Formulary Injection 
   
Terbutaline
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Formulary Injection 
   
07.02  Treatment of vaginal and vulval conditions
07.02.01  Preparations for vaginal and vulval changes
07.02.01  Topical HRT to top
Oestrogens, Topical (Gynest)
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Formulary 0.01% intravaginal cream 
   
Oestrogens, Topical (Vagifem)
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Formulary Vaginal tablets 
   
07.02.01  Non-hormonal preparations
07.02.02  Vaginal and vulval infections
07.02.02  Fungal infections
Clotrimazole
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First Choice Cream
Pessary 
Fluconazole
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First Choice Capsule 
Econazole
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Formulary Cream 
   
Ketoconazole 2%
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Formulary Cream 
   
Miconazole
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Formulary Cream 
Link  MHRA Safety Alert: serious interactions with warfarin
   
07.02.02  Other vaginal infections
Metronidazole
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First Choice Vaginal gel 
Clindamycin
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Second Choice Cream 
   
07.03  Contraceptives to top
07.03.01  Combined hormonal contraceptives
Loestrin 20  (Ethinylestradiol 20 mcg / norethisterone 1mg)
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First Choice Low strength preparation 
Microgynon 30 or Levest (Ethinylestradiol 30mcg / levonorgestrel 150mcg)
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First Choice Standard strength preparation 
Norimin  (Ethinylestradiol 35 mcg / noresthisterone 1mg)
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First Choice Standard strength preparation 
Ovysmen  (Ethinylestradiol 35 mcg / noresthisterone 500mcg)
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First Choice Standard strength preparation 
Microgynon 30 ED  (Ethinylestradiol 30 mcg / levonorgestrel 150 mcg)
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First Choice Standard strength, everyday preparation 
Logynon  (Ethinylestradiol / levonorgestrel phased pill)
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First Choice Tri-phasic preparation 
Cilest  (Ethinylestradiol 35 mcg / norgestimate 250 mcg)
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Second Choice Standard strength preparation 
   
TriNovum (Ethinylestradiol / norethisterone phased pill)
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Second Choice Tri-phasic preparation 
   
NuvaRing (Ethinylestradiol / etonogestrel)
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Formulary Low strength vaginal ring 
   
07.03.02  Progestogen-only contraceptives
Noriday  (Norethisterone 350mcg)
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First Choice  
Norgeston  (Levonorgestrel 30mcg)
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Formulary  
   
Micronor  (Norethisterone 350mcg)
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Formulary  
   
Zelleta (Desogestrel 75mcg)
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Formulary Tablets 
   
07.03.02.01  Oral progestogen-only contraceptives
07.03.02.02  Parenteral progestogen-only contraceptives
Etonorgestrel (Nexplanon)
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Formulary Implant 
   
Medroxyprogesterone Acetate (Depo-Provera)
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Formulary 12-weekly IM injection 
   
07.03.02.03  Intra-uterine progestogen-only contraceptive to top
Intra-uterine Progestogen Only System (Mirena)
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Formulary  
   
07.03.03  Spermicidal contraceptives
07.03.04  Contraceptive devices
07.03.04  Intra-uterine devices
Intra-uterine Contraceptive Devices (TT 380 Slimline®)
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Formulary  
   
07.03.04  Other contraceptive devices
07.03.05  Emergency Contraception to top
07.03.05  Hormonal methods
Levonorgestrel (Levonelle 1500)
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First Choice  
Ulipristal (EllaOne)
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Formulary  
   
07.03.05  Intra-uterine device
07.04  Drugs for genito-urinary disorders
07.04.01  Drugs for urinary retention
07.04.01  Alpha-blockers to top
Tamsulosin
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First Choice Capsules 
Alfuzosin
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Formulary M/R tablets 
   
Doxazosin
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Formulary Tablets 
Link  UKMI Q&A: How should conversion between doxazosin formulations be carried out?
   
07.04.01  Parasympathomimetics
07.04.02  Drugs for urinary frequency, enuresis, and incontinence
 note  GMMMG Guidance: Treatment of Overactive Bladder in Women



07.04.02  Urinary incontinence
Oxybutynin
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First Choice Tablets
M/R tablets
Patches (Restricted Item only when the oral route is not tolerated) 
Tolterodine
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First Choice Tablets
M/R capsules 
Trospium
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Second Choice Tablets
M/R capsules 
   
Mirabegron
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Third Choice M/R tablets

Only recommended if antimuscarinic drugs are contraindicated, clinically ineffective or have unacceptable side effects. 
Link  MHRA Safety Alert: Risk of severe hypertension and associated cerebrovascular and cardiac events
Link  NICE TA290: Mirabegron for overactive bladder
   
Solifenacin
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Third Choice Tablets 
   
Fesoterodine
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Third Choice M/R Tablets 
   
Duloxetine (Yentreve)
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Formulary Capsules

For stress incontinence only 
   
07.04.02  Nocturnal enuresis
Imipramine
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Formulary Tablets
Oral solution 
   
07.04.03  Drugs used in urological pain to top
07.04.03  Alkalinisation of urine
Potassium Citrate Mixture BP
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Formulary Oral solution 
   
Sodium Bicarbonate
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Formulary Capsules
Tablets 
   
07.04.03  Acidification of urine
07.04.03  Other preparations for urinary disorders
07.04.04  Bladder instillations and urological surgery
07.04.04  Urological surgery to top
Glycine 1.5%
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Formulary Bladder irrigation solution 
   
07.04.04  Maintenance of indwelling urinary catheters
Catheter Patency Solutions (Sodium Chloride 0.9% Uro-Tainer)
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Formulary  
   
Catheter Patency Solutions (Solution R Uro-Tainer)
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Formulary  
   
07.04.04  Bladder carcinoma
BCG (Bacillus Calmette-Guerin)
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Formulary Bladder instillation 
   
Cytotoxic Drug Doxorubicin
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Formulary Bladder instillation

note Liaise with Pharmacy Aseptics for preparation of this product 
   
Cytotoxic Drug Epirubicin
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Formulary Bladder instillation

note Liaise with Pharmacy Aseptics for preparation of this product 
   
Cytotoxic Drug Mitomycin
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Formulary Bladder instillation 
   
07.04.04  Interstitial cystitis
Dimethyl Sulfoxide 50% (Rimso-50)
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Formulary Bladder instillation 
   
07.04.05  Drugs for erectile dysfunction
07.04.05  Alprostadil to top
Alprostadil
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Formulary Caverject intracavernosal injection
MUSE urethral application 
   
07.04.05  Phosphodiesterase type 5 inhibitors
Sildenafil
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Formulary
Green 1
Tablets 
   
07.04.06  Drugs for premature ejaculation
07.04.06  Dapoxetine
 ....
 Non Formulary Items
Alprostadil  (Prostin VR)

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Non Formulary
 
Alprostadil  (Viridal® Duo)

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Non Formulary
 
Anethol, Borneol, Camphene, Cineole, Fenchone, Pinene  (Rowatinex)

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Non Formulary
 
Avanafil  (Stendra®)

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Non Formulary
 
Bethanechol Chloride  (Myotonine®)

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Non Formulary
 
Carbetocin  (Pabel®)

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Non Formulary
 
Combined Hormonal Contraceptives  (BiNovum®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Evra)

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Non Formulary
 
Combined Hormonal Contraceptives  (Femodene ED)

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Non Formulary
 
Combined Hormonal Contraceptives  (Loestrin 30)

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Non Formulary
 
Combined Hormonal Contraceptives  (Logynon ED)

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Non Formulary
 
Combined Hormonal Contraceptives  (Minulet®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Norinyl-1®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Qlaira®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Synphase®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Triadene®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Tri-minulet®)

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Non Formulary
 
Combined Hormonal Contraceptives  (Trinordiol®)

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Non Formulary
 
Dapoxetine  (Priligy)

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Non Formulary
 
Darifenacin  (Emselex)

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Non Formulary
 
Distigmine Bromide  (Ubretid)

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Non Formulary
 
Dutasteride and Tamsulosin  (Combodart)

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Non Formulary
 
Ethinylestradiol 20mcg / desogestrel 150mcg  (Gedarel, Mercilon)

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Non Formulary
 
Ethinylestradiol 20mcg / gestodene 75 mcg  (Millinette, Femodette)

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Non Formulary
 
Ethinylestradiol 30 mcg / drospirenone 3 mg  (Yasmin)

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Non Formulary
 
Ethinylestradiol 30 mcg / levonorgestrel 150 mcg  (Ovranette)

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Non Formulary
 
Ethinylestradiol 30mcg / desogestrel 150mcg  (Gedarel, Marvelon)

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Non Formulary
 
Ethinylestradiol 30mcg / gestodene 75 mcg  (Millinette, Femodene)

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Non Formulary
 
Fenticonazole  (Gynoxin)

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Non Formulary
 
Flavoxate

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Non Formulary
 
Indoramin  (Doralese)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (Flexi-T® + 300)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (Flexi-T® 300)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (GyneFix®)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (Load® 375)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (Nova-T® 360)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (T-Safe® CU 380 A)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (UT 380 Short®)

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Non Formulary
 
Intra-uterine Contraceptive Devices  (UT 380 Standard®)

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Non Formulary
 
Lactic acid  (Balance Activ Rx®)

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Non Formulary
 
Medroxyprogesterone acetate  (Sayana Press)

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Non Formulary
 
nomegestrol acetate and beta estradiol  (Zoely)

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Non Formulary
 
Norethisterone enantate  (Noristerat)

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Non Formulary
 
Oestrogens, Topical  (Estring)

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Non Formulary
 
Oestrogens, Topical  (Ovestin)

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Non Formulary
 
Oral Progestogen Only Contraceptives  (Cerazette, Cerelle)

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Non Formulary
 
Oral Progestogen-Only Contraceptives  (Femulen®)

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Non Formulary
 
Prazosin

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Non Formulary
 
Propantheline

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Non Formulary
 
Propiverine

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Non Formulary
 
Replens MD

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Non Formulary
 
Ritodrine  (Yutopar)

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Non Formulary
 
Spremicidal Contraceptives  (Ortho-Creme®)

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Non Formulary
 
Spremicidal Contraceptives  (Orthoforms®)

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Non Formulary
 
Tadalafil  (Cialis)

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Non Formulary
 
Terazosin

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Non Formulary
 
Vardenafil  (Levitra)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Drugs designated amber are suitable for shared care arrangements under a shared care protocol. Prescribing may be transferred from secondary to primary care once the patient is stabilised and agreed shared care arrangements have been established. Alternatively primary care may initiate under the supervision of secondary care if this option is given in the shared care document. It is recommended that shared care arrangements should be drawn up following local discussion and agreement by prescribing parties.   

Black

These products have been reviewed by the GM Joint Formulary Group and have been deemed not suitable for prescribing for adults in primary or secondary care within Greater Manchester. These decisions have been made on the basis of safety, efficacy and cost-effectiveness of the products.  

Green

Not used   

Green 1

Drugs designated green1 are suitable for initiation and ongoing prescribing within primary care.   

Green 2

Drugs designated green2 can be initiated by primary care following written or verbal advice from a specialist and then be subsequently safely prescribed in primary care with little or no monitoring required.  

Green 3

Drugs designated green3 are suitable for on-going prescribing within primary care after specialist initiation and an initial review (unless specified) in secondary care. Little or no monitoring is required.  

Grey

Not suitable for routine prescribing but may be suitable for a defined patient population. Whilst prescribers should think very carefully before prescribing or recommending any of the products on the grey list, there may be exceptional instances when the use of one of these products is necessary for a particular patient.   

Red

Drugs designated red are considered to be specialist medicines and prescribing responsibility for these medicines should normally remain with the consultant or specialist clinician. These drugs should not be initiated or prescribed in primary care. It is recommended that the supply of these specialist medicines should be organised via the hospital pharmacy, this may include arranging for supply via a home care company.   

netFormulary