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 Formulary Chapter 2: Cardiovascular system - Full Chapter
02.12  Expand sub section  Lipid-regulating drugs
02.12  Expand sub section  Statins
02.12  Expand sub section  Bile acid sequestrants
02.12  Expand sub section  Ezetimibe
02.12  Expand sub section  Fibrates to top
02.12  Expand sub section  Nicotinic acid group
02.12  Expand sub section  Omega-3 fatty acid compounds
02.12  Expand sub section  Other lipid modifying agents
Evolocumab (Repatha®)

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First Choice
High Cost Medicine
Red
Pre-filled syringe
Pre-filled pen

Only as per NICE TA394.
Requires completion of Blueteq form prior to initiation.
Available via Homecare providers.



Link  NICE TA394: Evolocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
Link  GMMMG Pathway: PCSK9 inhibitors in the treatment of hypercholesterolaemia  
Alirocumab (Praluent®)

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Second Choice
High Cost Medicine
Red
Pre-filled syringe
Pre-filled pen

Restricted Item For patients with latex allergy or intolerance to evolocumab

Only as per NICE TA393.
Requires completion of Blueteq form prior to initiation.
Available via Homecare providers.



Link  NICE TA393: Alirocumab for treating primary hypercholesterolaemia and mixed dyslipidaemia
Link  GMMMG Pathway: PCSK9 inhibitors in the treatment of hypercholesterolaemia  
 ....
Key
note Notes First Choice Item First Choice item
Section Title Section Title (top level) Non Formulary Item Non Formulary section
Section Title Section Title (sub level)
Cytotoxic Drug
Cytotoxic Drug
Restricted Drug
Restricted Drug
CD
Controlled Drug
Unlicensed Drug
Unlicensed
High Cost Medicine
High Cost Medicine
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Link to SPCs
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Link to adult BNF
Track Changes
Display tracking information
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Link to children's BNF
Cancer Drugs Fund
Cancer Drugs Fund
   

 

Traffic Light Status Information

Status Description
  Amber   Drugs designated amber are suitable for shared care arrangements under a shared care protocol. Prescribing may be transferred from secondary to primary care once the patient is stabilised and agreed shared care arrangements have been established. Alternatively primary care may initiate under the supervision of secondary care if this option is given in the shared care document. It is recommended that shared care arrangements should be drawn up following local discussion and agreement by prescribing parties.   
  Black   These products have been reviewed by the GM Joint Formulary Group and have been deemed not suitable for prescribing for adults in primary or secondary care within Greater Manchester. These decisions have been made on the basis of safety, efficacy and cost-effectiveness of the products.  
  Green   Not used   
  Green 1   Drugs designated green1 are suitable for initiation and ongoing prescribing within primary care.   
  Green 2   Drugs designated green2 can be initiated by primary care following written or verbal advice from a specialist and then be subsequently safely prescribed in primary care with little or no monitoring required.  
  Green 3   Drugs designated green3 are suitable for on-going prescribing within primary care after specialist initiation and an initial review (unless specified) in secondary care. Little or no monitoring is required.  
  Grey   Not suitable for routine prescribing but may be suitable for a defined patient population. Whilst prescribers should think very carefully before prescribing or recommending any of the products on the grey list, there may be exceptional instances when the use of one of these products is necessary for a particular patient.   
  Red   Drugs designated red are considered to be specialist medicines and prescribing responsibility for these medicines should normally remain with the consultant or specialist clinician. These drugs should not be initiated or prescribed in primary care. It is recommended that the supply of these specialist medicines should be organised via the hospital pharmacy, this may include arranging for supply via a home care company.   

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